The Analytical Toxicology Core Laboratory provides support to all researchers requiring qualitative and/or quantitative chemical analysis to accomplish their study objectives. Equipped with state-of-the-art instrumentation and staffed with personnel experienced in handling complex biological tissues, the ATCL is an available resource for method development, as well as for routine analyses. In support of the Superfund Program, routine work has included the analysis of organochlorine pesticides, polyaromatic hydrocarbons, and polychlorinated biphenyls from both low and high lipid matrices via GC-MS, along with the analysis of isoflavones from culture media, cell pellets, and commercial food products via HPLC-UV-MS. In addition to the above methods (the development and validation of which were originally funded by this program), the ATCL has also provided molecular weight determinations of proteins, fatty acid profiles for reproductive tissues, the identification and quantitation of estrogenic and androgenic species in various matrices, and other analyses as requested by program participants.

The Aquatic Toxicology Core Facility provides technical expertise and facilities for the rearing, holding and toxicological testing of aquatic organisms. The aquatic core facility has the capability to house multiple aquatic species and to conduct acute and chronic studies. Project investigators will work with the aquatic core manager in the design and execution of all in vivo aquatic studies.